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mutations and complicated kar yotype. It follows a linear evolution from your CLL clone from the recurrent acquisition of CDKN2A
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gene in people relapsing following therapy Along with the BCL2 antagonist venetoclax. 66 Resistance to those brokers has become affiliated with these mutations in all over 70% of instances, Even though they usually are subclonal as well as their precise role causing resistance has to be confirmed.
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